Link to publication
Year of Selection & Year of Publication: 2012 & 2016
Paragraph on background/aims and objectives:
The ETPOS study aims to describe differences in transfusion habits throughout Europe and to correlate these habits to perioperative outcome parameters. Particular focus is put on the number of PRBCs transfused and the ratio of PRBCs to other blood products or coagulation factors in the operating room. Furthermore, the motivation of physicians to transfuse PRBC and blood products in the operating room will be investigated.
In European patients undergoing elective non-cardiac surgery receiving at least one PRBC during their operation, it is proposed to:
- Evaluate evidence of differences in the standard of perioperative transfusion care in different healthcare systems within Europe, and the use of blood conserving techniques.
- Evaluate the ratio of transfusion of PRBC to blood products in the operating room
- Evaluate which factors determine transfusion of PRBC (is it patient’s haemodynamics/haemoglobin threshold / pressure from the surgeon / acute brisk bleeding / else) and blood products (ratio to PRBC / POC monitoring / per protocol / else) in the operating room.
- Evaluate whether there are factors in transfusion therapy that are associated with outcome (postoperative mortality within 30 days and unplanned admission to ICU).
List of Chief investigator and Steering Committee members
|Assoc. Prof. Dr Daniela Filipescu||Emergency Institute of Cardiovascular Diseases
Sos. Fundeni no. 256, RO 022328 Bucharest, Romania
T: +402 131 724 72, Email
|Prof. Dr Sibylle Kozek Langenecker||EKH Evangelic Hospital Vienna
Department of Anesthesiology and Intensive Care Medicine, Hans-Sachs-Gasse 10-12, AU 1180, Vienna, Austria
T: +431 404 224 141, Email
|Prof. Dr Juan V. Llau Pitarch||Hospital Clínico Universitario de Valencia
Department of Anesthesiology and Intensive Care Medicine, Avenida Vicente Blasco Ibañez, ES 17 46010 Valencia, Spain
Telephone: +34 9638 62600, Email
|Dr Susan Mallett||Royal Free London NHS Foundation
Trust, Pond Street, NW3 2QG London, United Kingdom
T: +44 2077940500 Ext. 34454, M: +44 7860704684, Email
|Prof. Dr Peter Martus
|Department of Anesthesiology
Westbahnhofstraße 55, DE 72070 Tübingen, Germany
T: +49 7071-2986829, Email
|Prof. Dr Idit Matot||Tel Aviv Medical Centre
Department of Anesthesiology & Intensive Care Medicine & Pain, 6 Weizman Street, Tel Aviv, 64239, Israel
|Prof. Dr Jens Meier, MD
|University Hospital Tübingen
Department of Anesthesiology and Intensive Care Medicine, Hoppe-Seyler-Straße 3, DE 72076 Tübingen, Germany
T: +49 7071 2986619, Email
The ETPOS study is entirely sponsored by a grant of the European Society of Anaesthesiology Clinical Trial Network (ESA CTN).
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