Clinical Trial Network

About APRICOT

APRICOT: Anaesthesia PRactice In Children Observational Trial: European prospective multicenter observational study: Epidemiology of severe critical events

Primary endpoint

  • Incidence of severe critical events as an incidents occurring during and up to 60 minutes after anaesthesia or sedation (laryngospasm, bronchospasm, pulmonary aspiration, drug error, anaphylaxis, cardiovascular instability, neurological damage, cardiac arrest and post-extubation stridor) during and immediately following anaesthesia (PACU)

Secondary endpoints

  • Risk factors for the occurrence of severe critical events (up to 60 minutes afterwards).
  • Consequences of the critical events: no repercussion, minor aftermath, irreversible damage, in-hospital mortality up to 30 days or discharge.

APRICOT manuscript entitled “INCIDENCE OF SEVERE CRITICAL EVENTS IN PAEDIATRIC ANAESTHESIA:  A PROSPECTIVE MULTICENTRE OBSERVATIONAL STUDY IN 261 HOSPITALS IN EUROPE is on-line in The Lancet Respiratory Medicine as from Monday 28 March at 23 :30 pm.

Study is registered on ClinicalTrials.gov website: NCT01878760