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NCT01441791

Link to publication

Year of Selection & Year of Publication: 2011 & 2014

 

Paragraph on background/aims and objectives

Postoperative pulmonary complications, in particular after open abdominal surgery and general anaesthesia, add to the morbidity and mortality of surgical patients. Whether a mechanical ventilation strategy using higher levels of positive end-expiratory pressure (PEEP) and repeated recruitment manoeuvres protects against postoperative pulmonary complications is uncertain. The present study aims at comparing mechanical ventilation this protective strategy with conventional mechanical ventilation during nonlaparoscopic abdominal surgery and seeks to assess the effect on postoperative pulmonary complications.

 

List of Chief investigator and Steering Committee members

Marcus Schultz (Project leader) Academic Medical Center, University of Amsterdam, The Netherlands, Department of Intensive Care Medicine

Sabrine Hemmes, (Trial Coordinator) Academic Medical Center, University of Amsterdam, The Netherlands, Department of Intensive Care Medicine and Anesthesiology

Paolo Pelosi, University of Genoa, Genoa, Italy, Department of Surgical Sciences and Integrated Diagnostics

Marcelo Gama de Abreu, University Hospital Carl Gustav Carus, Dresden, Germany, Department of Anesthesiology and Intensive Care Medicine

Severgnini, University of Insubria, Varese, Italy, Department of Environment, Health and Safety

Jaber, Saint Eloi University Hospital, Montpellier, France, Department of Critical Care Medicine and Anesthesiology

Canet, Hospital Universitari Germans Trias I Pujol, Barcelona, Spain, Department of Anesthesiology

Wrigge, University of Leipzig, Germany, Department of Anesthesiology and Intensive Care Medicine

Hiesmayr, Medical University, Vienna, Austria, Division Cardiac-, Thoracic-, Vascular Anesthesia and Intensive Care

Tschernko, Medical University, Vienna, Austria, Division Cardiac-, Thoracic-, Vascular Anesthesia and Intensive Care

M.W. Hollmann, Academic Medical Center, University of Amsterdam, The Netherlands, Department of Anesthesiology

J.M. Binnekade, Academic Medical Center, University of Amsterdam, The Netherlands, Department of Intensive Care Medicine

Hedenstierna, University Hospital, Uppsala, Sweden, Department of Medical Sciences, Section of Clinical Physiology

Putensen, University Hospital, Bonn, Germany, Department of Anaesthesiology and Intensive Care Medicine

 

Sponsor:

The PROVHILO study is sponsored by the  Academisch Medisch Centrum – Universiteit van Amsterdam (AMC-UvA)

Contact email for more info => research@esahq.org