The ESA Research Committee has selected the following multi-centre studies to enter the ESA Clinical Trial Network (CTN). Your hospital may join one of the study listed below as a centre. The first step in this process is to apply to participate in one of the studies and become an ESA CTN active centre.
- EPiMAP Obstetrics: European Practices in the Management of Accidental dural Puncture in Obstetrics" Observational study. Chief Investigator Anil Gupta (Sweden) (study ongoing-protocol available)
- PLATA: Prevention of Phantom Limb Pain After Transtibial Amputation: Randomized, double-blind, controlled, multi-center trial comparing Optimized pain control vs Optimized pain control plus Nerve Block Interventional study Chief Investigator: Philipp Lirk (Netherlands) (study ongoing – protocol available)
- NECTARINE: NEonate-Children sTudy of Anaesthesia pRactice IN Europe Epidemiology of morbidity and mortality in neonatal anaesthesia: A European prospective multicentre observational study. Chief Investigator Nicola Disma (Italy) (study planned for 2016- protocol available)
- PROBESE: PRotective Ventilation with Higher versus Lower PEEP during General Anesthesia for Surgery in OBESE Patients – The PROBESE Randomized Controlled Trial. Chief Investigator Marcelo Gama de Abreu (Germany) (study ongoing-protocol available)
- The ESA CTN is open to all clinicians meeting study protocol criteria.
- Individuals and Institutions/Centres may participate in several studies of the ESA CTN at the same time.
- Centres throughout Europe are invited to participate in ESA CTN studies. Some studies are also open to non-European sites (study protocol specific).
- In case several individuals from the same department apply to participate in the same study, only one person for each centre will be appointed as responsible for the centre and will be referred to as ‘Local Coordinator’. The role and responsibilities of the Local Coordinator are detailed under Guidance (GUI-CTN-002 Local Coordinator Role Guidelines).
- If several departments from the same institution apply to participate in a CTN study and if these departments have buildings at different locations, it may be possible to consider the 2 locations as 2 separate study sites.
- For all ESA Sponsored studies, at least one person of the Institution taking part in the CTN study must be an ESA member and will be required to provide an ESA membership number. The Research Committee suggests that either the Local Coordinator and/or the Head of the department (preferably both and even more colleagues from the department) become a member of the ESA in order to ensure that there is at least one ESA member as collaborator for the research publication of the study per CTN centre.
You are invited to submit contact details on behalf of your hospital in order to become an ESA CTN centre participating in one or more studies.
- Completion of the Online Call for Centres Form will facilitate coordination and is mandatory for registering the Institution’s participation in an ESA CTN study.
- For the UK, the study protocol registration process has already been submitted to the NIHR authorities, therefore any further British hospitals registering after 21 February 2016 will be put on a waiting list. Then it is planned to have an “amendment” in June with addition of new centres in UK who have registered from 22 February to 15 June 2016.
- All fields on the ‘Call for Centres form’ marked with an asterisk are mandatory. When ESA is the study sponsor, the Local Coordinator will be asked to provide 1 current ESA membership per institution (all types of ESA membership are accepted: active, associate, affiliate, trainee, etc.) More information can be found here, for advantages resulting from the various membership types, please refer to the ESA membership section.
- The ESA Secretariat will acknowledge receipt of the ‘Call for Centres form’ and will contact centres providing them with additional study information.